erectile dysfunction medicine
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Erectile Dysfunction (ED) affects more than 18 million men in the U.S alone. Most of these men are over 40 years old, although it can strike you no matter what your age may be. ED is sometimes an unfortunate side effect of a disease. Men who have diabetes, decreased testosterone levels, high blood pressure, an enlarged prostate, may get ED. Smoking, alcohol misuse, or certain medications can also cause ED. It can even be the result of everyday pressures such as anxiety or stress. Fortunately, no matter what the cause, Erectile Dysfunction can be successfully treated.
While some men respond well to oral ED treatments such as Viagra or Cialis, others have uncomfortable or even dangerous side effects to these medications. In those cases, custom compounded medications can be used successfully to treat ED.
Oral ED Medications
Viagra (Sildenafil)
Another medicine we use to help patients address ED is Viagra. This is available as an oral tablet ranging from 25 mg to 100 mg. A starting dose of 50 Mg taken about one hour prior to sexual intercourse has been recommended8. Viagra has been reported as a safe and efficacious treatment for ED, however, it is ineffective in approximately 27 to 35% of the population and has been associated with a variety of adverse effects including headache, flushing, dyspepsia, and adverse interaction with nitrates and inhibitors of cytochrome P450 enzymes. Viagra should not be taken in conjunction with nitrate therapy.
Oral ED Medication
Cialis (Tadalafil)
Cialis is another oral tablet we offer at our clinic in West Bloomfield, ranging from 5 to 20 mg. The recommended tadalafil starting dose for most men is 10 mg, taken as needed before sexual activity (but not more than once daily). The dose may be increased to 20 mg or decreased to 5 mg, per its efficacy and the man’s personal tolerance of the drug. Cialis’s 36-hour effectiveness earned it the nickname, “The Weekend Pill”; like sildenafil, tadalafil is recommended as an ‘as needed’ medication. Cialis is the only one of the three that is also offered as a once-daily medication.
ED Medications Available
Injections
One erectile dysfunction medicine we offer at Cratus Medical Vitality Institute in West Bloomfield comes in the form of injections. The injectable medications we use, including Papaverine, Phentolamine, Alprostadil (Prostaglandin E1) the three of which are also called Trimix, as well as Atropine, Chlorpromazine, and/or Forskolin can either be administered individually or in combination. While an injectable ED medication may sound intimidating or even painful, the treatment involves very little discomfort and is an easy and very effective way to treat ED.
Dr. Quinn offers 2 services that can be used alone or in combination with other treatment modalities—the P-Shot and GainsWave. Dr. Quinn is one of only a handful of physicians in the state of Michigan to be certified to perform both procedures.
Additional Information Regarding Tri-mix
General Information
Tri-mix is administered as a penile self-injection, typically considered to be the most powerful class of anti-erectile dysfunction agents. While the components of Tri-mix are, on there own, indicated for a vast number of different conditions (papaverine, phentolamine, PGE1 monographs), the practice of bringing them together in concert to treat erectile dysfunction has become commonplace in sexual medicine and is now considered to be the go-to treatment if conventional PDE5 inhibitors are contraindicated or nonresponsive. and is now considered the go-to treatment if a patient is not responsive to conventional PDE5 inhibitors such as Viagra or Cialis.
Trimix FAQ
- Are there reasons not to take this medicine?
Do not take this medicine with any of the following medications: hypersensitivity or allergy to any component of this formulation; conditions predisposing you to priapism (painful erection lasting 4 hours or more): sickle cell anemia, multiple myeloma or leukemia; anatomical deformation of the penis or penile implants; direction by your physician that sexual activity is inadvisable or contraindicated
- Key warnings before taking this medicine?
Tell your doctor if you have a condition or are taking a medicine that interferes with blood clotting.
- What are the precautions when taking this medicine?
Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Some items may interact with your medicine.
- How is it best taken?
Ideally, the injection should be administered just prior to foreplay. It is administered via intravavernosal injection and should produce an erection in 5 to 20 minutes and can be expected to last up to one hour. To prevent bruising, apply firm pressure to the injection site for 5 minutes after injecting. Do not use Tri-mix Injection more than two times a week; use at least 24 hours apart. There is a possibility of needle breakage with use of Tri-mix Injection: you should pay careful attention to your doctor’s instructions and handle syringe and needle properly. If the needle breaks during injection, you should promptly contact your doctor.
- What do I do if I miss a dose?
Do not take double or extra doses. This medicine should only be taken 5 to 20 minutes before intercourse.
- What are some possible side effects of this medicine?
Mild to moderate pain during injection; painful sensation with erection; small amount of bleeding at the injection site. Call your healthcare provider if you notice any redness, lumps, swelling, tenderness or curvature of the erect penis. If you experience an erection lasting more than 2 hours, you may take 2 – 4 pseudoephedrine 30 mg by mouth once and apply an ice pack. If your erection does not go away within the next hour, seek professional help immediately. Erections that last more than 6 hours can cause serious damage to the penile tissue.
- How should I store this medicine?
The mixture is not stable for long periods at room temperature. Once reconstituted keep this medicine in a refrigerator below 41°F (5°C). It is important to note that improper storage does not result in harmful chemicals: the only thing to suffer is the potency – the preparation may not be as strong as when fresh. Keep all medicine out of the reach of children. Throw away any unused medicine after the expiration date. Do not flush unused medications or pour down a sink or drain.
- General statements
Do not share or take any one else’s medicine. Talk with your healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins. This medication was compounded specifically for you. This patient information summarizes the most important information about your medication; if you would like more information, talk with your doctor.
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